Pseudomonas aeruginosa PAO1, PA0051 (phzH)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0003824	catalytic activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0002047	phenazine biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Molecular Function	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR01536	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006529	asparagine biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR01536	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	PWY-7221	guanosine ribonucleotides de novo biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	PWYB-5652	Phenazine biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae00250	Alanine, aspartate and glutamate metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Phenazine biosynthesis		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
NCBIfam	TIGR01536	JCVI: asparagine synthase (glutamine-hydrolyzing)	IPR006426	Asparagine synthase, glutamine-hydrolyzing	2	537	0.0
Pfam	PF00733	Asparagine synthase	IPR001962	Asparagine synthase	242	604	1.3E-81
PANTHER	PTHR43284	ASPARAGINE SYNTHETASE (GLUTAMINE-HYDROLYZING)	-	-	1	606	0.0
Pfam	PF13537	Glutamine amidotransferase domain	IPR017932	Glutamine amidotransferase type 2 domain	48	170	4.2E-43
SUPERFAMILY	SSF52402	Adenine nucleotide alpha hydrolases-like	-	-	231	578	7.85E-60
CDD	cd00712	AsnB	IPR033738	Asparagine synthase, N-terminal domain	2	225	3.51368E-100
CDD	cd01991	Asn_Synthase_B_C	IPR001962	Asparagine synthase	243	538	3.46535E-62
SUPERFAMILY	SSF56235	N-terminal nucleophile aminohydrolases (Ntn hydrolases)	IPR029055	Nucleophile aminohydrolases, N-terminal	1	226	9.44E-62
PIRSF	PIRSF001589	Asn_synthetase_glu-h	IPR006426	Asparagine synthase, glutamine-hydrolyzing	1	610	0.0
Gene3D	G3DSA:3.60.20.10	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	IPR029055	Nucleophile aminohydrolases, N-terminal	11	223	1.1E-59
Gene3D	G3DSA:3.40.50.620	HUPs	IPR014729	Rossmann-like alpha/beta/alpha sandwich fold	224	591	1.4E-59

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.