Pseudomonas aeruginosa PAO1, PA0051 (phzH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0051
Name
phzH
Replicon chromosome
Genomic location 66303 - 68135 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248741.1
GI 15595249
Affymetrix PA0051_at
Entrez 878637
GenBank AAG03441.1
INSDC AAG03441.1
NCBI Locus Tag PA0051
protein_id(GenBank) gb|AAG03441.1|AE004445_2|gnl|PseudoCAP|PA0051
TIGR NTL03PA00052
UniParc UPI00000C4F05
UniProtKB Acc Q9I781
UniProtKB ID Q9I781_PSEAE
UniRef100 UniRef100_Q9I781
UniRef50 UniRef50_A0A075UWI4
UniRef90 UniRef90_Q9I781

Product

Feature Type CDS
Coding Frame 1
Product Name
potential phenazine-modifying enzyme
Product Name Confidence: Class 2
Synonyms probable glutamine amidotransferase
Evidence for Translation
Charge (pH 7) -1.16
Kyte-Doolittle Hydrophobicity Value -0.353
Molecular Weight (kDa) 69.5
Isoelectric Point (pI) 6.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0100
Category Phenazine biosynthesis
Evidence ECO:0000305
curator inference used in manual assertion
Host Organism Mus musculus
Notes
Reference 11591691

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 439 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000051 (310 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0051
Search term: phzH

Human Homologs

References

Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1.
Mavrodi DV, Bonsall RF, Delaney SM, Soule MJ, Phillips G, Thomashow LS
J Bacteriol 2001 Nov;183(21):6454-65
PubMed ID: 11591691