Pseudomonas aeruginosa PAK, PAK_00262 (exoT)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAK - Assembly GCF_000408865.1
GCF_000408865.1|latest |
| Locus Tag |
PAK_00262
|
| Name |
exoT
|
| Replicon | chromosome |
| Genomic location | 291528 - 292901 (+ strand) |
Cross-References
| RefSeq | WP_016252826.1 |
| GI | 510932460 |
| NCBI Locus Tag | PAK_00262 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
exoenzyme T
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -8.32 |
| Kyte-Doolittle Hydrophobicity Value | -0.314 |
| Molecular Weight (kDa) | 48.5 |
| Isoelectric Point (pI) | 5.66 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 6GNN | TOXIN | 05/31/18 | Exoenzyme T from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, tetrameric crystal form bound to STO1101 | Homo sapiens; Pseudomonas aeruginosa PAO1 | 3.79 | X-RAY DIFFRACTION | 100.0 |
| 6JNP | TOXIN | 03/17/19 | Structure of ExoT-SpcS Complex from Pseudomonas aeruginosa in 2.2 Angstrom | Pseudomonas aeruginosa | 2.261 | X-RAY DIFFRACTION | 98.2 |
| 4JMF | TOXIN/CHAPERONE | 03/14/13 | Crystal structure of ExoT (residues 28 -77)- SpcS complex from Pseudomonas aeruginosa at 2.1 angstrom | Pseudomonas aeruginosa | 2.099 | X-RAY DIFFRACTION | 100.0 |
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000044 (294 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PAK_00262
Search term: exoT
Search term: exoenzyme T
|
Human Homologs
References
No references are associated with this feature.