Pseudomonas aeruginosa PAO1, PA0074 (ppkA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0050714 positive regulation of protein secretion
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
19400797 Reviewed by curator
Molecular Function GO:0004674 protein serine/threonine kinase activity
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
9852028 Reviewed by curator
Biological Process GO:0006468 protein phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00108
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004672 protein kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00108
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50011
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Protein secretion/export apparatus Other PAO1 genes in this class
Adaptation, Protection Other PAO1 genes in this class
Translation, post-translational modification, degradation Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae03070 Bacterial secretion system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00198 vWFA 616 797 2.65391E-12
ProSiteProfiles PS50011 Protein kinase domain profile. IPR000719 Protein kinase domain 8 262 42.379
Gene3D G3DSA:3.30.200.20 2 87 3.0E-28
MobiDBLite mobidb-lite consensus disorder prediction 316 347 -
Gene3D G3DSA:3.40.50.410 IPR036465 von Willebrand factor A-like domain superfamily 613 809 1.2E-11
SMART SM00220 IPR000719 Protein kinase domain 8 263 5.1E-66
MobiDBLite mobidb-lite consensus disorder prediction 276 351 -
ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. IPR008271 Serine/threonine-protein kinase, active site 125 137 -
CDD cd14014 STKc_PknB_like 7 261 6.48413E-108
SMART SM00327 IPR002035 von Willebrand factor, type A 613 804 2.5E-9
Pfam PF00092 von Willebrand factor type A domain IPR002035 von Willebrand factor, type A 616 780 1.2E-5
ProSiteProfiles PS50234 VWFA domain profile. IPR002035 von Willebrand factor, type A 615 818 9.408
Pfam PF00069 Protein kinase domain IPR000719 Protein kinase domain 9 250 4.1E-50
SUPERFAMILY SSF56112 IPR011009 Protein kinase-like domain superfamily 6 339 1.48E-76
SUPERFAMILY SSF53300 IPR036465 von Willebrand factor A-like domain superfamily 615 793 2.23E-12
ProSitePatterns PS00107 Protein kinases ATP-binding region signature. IPR017441 Protein kinase, ATP binding site 14 37 -
MobiDBLite mobidb-lite consensus disorder prediction 381 417 -
MobiDBLite mobidb-lite consensus disorder prediction 586 606 -
MobiDBLite mobidb-lite consensus disorder prediction 281 299 -
Gene3D G3DSA:1.10.510.10 88 274 3.8E-47

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.