Pseudomonas aeruginosa PAO1, PA0228 (pcaF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0044255 cellular lipid metabolic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Biological Process GO:0044248 cellular catabolic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Biological Process GO:0015976 carbon utilization
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Molecular Function GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00108
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019619 3,4-dihydroxybenzoate catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02430
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53901
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008152 metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00108
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Fatty acid and phospholipid metabolism Other PAO1 genes in this class
Carbon compound catabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00362 Benzoate degradation 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Aromatic compound catabolism ECO:0000037
not_recorded
KEGG (InterPro) 00362 Benzoate degradation InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.47.10 IPR016039 Thiolase-like 283 397 3.5E-160
Pfam PF02803 Thiolase, C-terminal domain IPR020617 Thiolase, C-terminal 277 400 6.9E-43
Gene3D G3DSA:3.40.47.10 IPR016039 Thiolase-like 7 141 3.5E-160
Gene3D G3DSA:3.40.47.10 IPR016039 Thiolase-like 201 282 3.5E-160
ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. IPR020615 Thiolase, acyl-enzyme intermediate active site 87 105 -
CDD cd00751 thiolase IPR002155 Thiolase 6 400 0.0
SUPERFAMILY SSF53901 IPR016039 Thiolase-like 277 400 3.12E-45
SUPERFAMILY SSF53901 IPR016039 Thiolase-like 4 276 4.51E-88
PIRSF PIRSF000429 IPR002155 Thiolase 1 401 9.7E-136
Gene3D G3DSA:3.40.47.10 IPR016039 Thiolase-like 142 200 3.5E-160
ProSitePatterns PS00737 Thiolases signature 2. IPR020613 Thiolase, conserved site 347 363 -
TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase IPR002155 Thiolase 7 399 1.0E-138
ProSitePatterns PS00099 Thiolases active site. IPR020610 Thiolase, active site 382 395 -
Pfam PF00108 Thiolase, N-terminal domain IPR020616 Thiolase, N-terminal 5 268 4.7E-79
TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase IPR012793 Beta-ketoadipyl CoA thiolase 3 401 8.3E-224

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.