Pseudomonas aeruginosa PAO1, PA0510 (nirE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009108 obsolete coenzyme biosynthetic process
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
19754882 Reviewed by curator
Molecular Function GO:0008168 methyltransferase activity
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
19754882 Reviewed by curator
Biological Process GO:0009061 anaerobic respiration
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
8982003 Reviewed by curator
Biological Process GO:0006783 heme biosynthetic process
IMP
Inferred from Mutant Phenotype
ECO:0000016
loss-of-function mutant phenotype evidence
8982003 Reviewed by curator
Biological Process GO:0019354 siroheme biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01469
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008168 methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01469
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class
Energy metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-7376 cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc P381-PWY adenosylcobalamin biosynthesis II (late cobalt incorporation) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae00860 Porphyrin and chlorophyll metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Biosynthesis of heme d1 ECO:0000037
not_recorded
PseudoCAP Denitrification ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.40.1010.10:FF:000001 Siroheme synthase - - 14 133 8.1E-51
CDD cd11642 SUMT IPR006366 Uroporphyrin-III C-methyltransferase 23 251 1.97273E-128
Gene3D G3DSA:3.30.950.10 - IPR014776 Tetrapyrrole methylase, subdomain 2 134 266 2.9E-50
NCBIfam TIGR01469 JCVI: uroporphyrinogen-III C-methyltransferase IPR006366 Uroporphyrin-III C-methyltransferase 18 253 8.7E-94
PANTHER PTHR45790 SIROHEME SYNTHASE-RELATED - - 17 254 1.9E-95
Gene3D G3DSA:3.40.1010.10 - IPR014777 Tetrapyrrole methylase, subdomain 1 11 133 4.0E-43
Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases IPR000878 Tetrapyrrole methylase 20 230 4.5E-49
SUPERFAMILY SSF53790 Tetrapyrrole methylase IPR035996 Tetrapyrrole methylase superfamily 14 263 2.09E-82
FunFam G3DSA:3.30.950.10:FF:000001 Siroheme synthase - - 134 266 3.0E-48

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.