Pseudomonas aeruginosa PAO1, PA0546 (metK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00086
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004478 methionine adenosyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00086
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006556 S-adenosylmethionine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00086
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class
Central intermediary metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Selenoamino acid metabolism ECO:0000037
not_recorded
PseudoCyc PWY-802 methionine and S-adenosylmethionine synthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00270 Cysteine and methionine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Methionine metabolism ECO:0000037
not_recorded
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR01034 JCVI: methionine adenosyltransferase IPR002133 S-adenosylmethionine synthetase 6 392 0.0
Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain IPR022630 S-adenosylmethionine synthetase, C-terminal 234 367 2.4E-67
Gene3D G3DSA:3.30.300.10 - - - 12 271 0.0
SUPERFAMILY SSF55973 S-adenosylmethionine synthetase IPR022636 S-adenosylmethionine synthetase superfamily 112 233 8.24E-50
SUPERFAMILY SSF55973 S-adenosylmethionine synthetase IPR022636 S-adenosylmethionine synthetase superfamily 6 110 2.2E-44
Hamap MF_00086 S-adenosylmethionine synthase [metK]. IPR002133 S-adenosylmethionine synthetase 3 394 55.902611
PANTHER PTHR11964 S-ADENOSYLMETHIONINE SYNTHETASE IPR002133 S-adenosylmethionine synthetase 4 388 0.0
FunFam G3DSA:3.30.300.10:FF:000003 S-adenosylmethionine synthase - - 135 235 1.5E-36
Gene3D G3DSA:3.30.300.10 - - - 6 234 0.0
Pfam PF02772 S-adenosylmethionine synthetase, central domain IPR022629 S-adenosylmethionine synthetase, central domain 115 232 2.5E-43
PIRSF PIRSF000497 MAT IPR002133 S-adenosylmethionine synthetase 1 394 0.0
Gene3D G3DSA:3.30.300.10 - - - 104 387 0.0
CDD cd18079 S-AdoMet_synt - - 7 385 0.0
SUPERFAMILY SSF55973 S-adenosylmethionine synthetase IPR022636 S-adenosylmethionine synthetase superfamily 234 395 3.26E-67
Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain IPR022628 S-adenosylmethionine synthetase, N-terminal 6 101 5.5E-40

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.