Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1509
|
Name |
tplEi
Synonym: tli4 |
Replicon | chromosome |
Genomic location | 1638652 - 1639794 (- strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_250200.1 |
GI | 15596706 |
Affymetrix | PA1509_at |
Entrez | 879385 |
GenBank | AAG04898.1 |
INSDC | AAG04898.1 |
NCBI Locus Tag | PA1509 |
protein_id(GenBank) | gb|AAG04898.1|AE004579_10|gnl|PseudoCAP|PA1509 |
TIGR | NTL03PA01510 |
UniParc | UPI00000C53B6 |
UniProtKB Acc | Q9I3K3 |
UniProtKB ID | Q9I3K3_PSEAE |
UniRef100 | UniRef100_Q9I3K3 |
UniRef50 | UniRef50_Q9I3K3 |
UniRef90 | UniRef90_Q9I3K3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
immunity protein, TplEi
|
Synonyms |
Tli4 |
Evidence for Translation | |
Charge (pH 7) | -0.91 |
Kyte-Doolittle Hydrophobicity Value | -0.481 |
Molecular Weight (kDa) | 42.4 |
Isoelectric Point (pI) | 6.80 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
5H7Z | HYDROLASE INHIBITOR | 11/21/16 | Apo structure of immunity protein TplEi of T6SS from Pseudomonas aeruginosa | Pseudomonas aeruginosa PAO1 | 3.057 | X-RAY DIFFRACTION | 100.0 |
5H7Y | HYDROLASE INHIBITOR/PEPTIDE | 11/21/16 | Structure of immunity protein TplEi of T6SS from Pseudomonas aeruginosa complexed with L peptide | Pseudomonas aeruginosa PAO1 | 2.195 | X-RAY DIFFRACTION | 100.0 |
4R1D | HYDROLASE/HYDROLASE INHIBITOR | 08/05/14 | The crystal structure of Tle4-Tli4 complex | Pseudomonas aeruginosa PAO1 | 1.749 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 11 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003846 (288 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1509
Search term: tplEi
Search term: immunity protein, TplEi
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors.
Russell AB, LeRoux M, Hathazi K, Agnello DM, Ishikawa T, Wiggins PA, Wai SN, Mougous JD
Nature 2013 Apr 25;496(7446):508-12
PubMed ID: 23552891
|
The Pseudomonas aeruginosa Type VI Secretion PGAP1-like Effector Induces Host Autophagy by Activating Endoplasmic Reticulum Stress.
Jiang F, Wang X, Wang B, Chen L, Zhao Z, Waterfield NR, Yang G, Jin Q
Cell Rep 2016 Aug 9;16(6):1502-1509
PubMed ID: 27477276
|