Pseudomonas aeruginosa PAO1, PA1823 (nudC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016787 hydrolase activity
IMP
Inferred from Mutant Phenotype 		ECO:0000315
mutant phenotype evidence used in manual assertion		 24989777 Reviewed by curator
Molecular Function GO:0046872 metal ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF09297
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF09296
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000210 NAD+ diphosphatase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00297
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Hypothetical, unclassified, unknown Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00760 Nicotinate and nicotinamide metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF09297 NADH pyrophosphatase zinc ribbon domain IPR015376 Zinc ribbon, NADH pyrophosphatase 109 140 1.8E-11
Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain IPR015375 NADH pyrophosphatase-like, N-terminal 19 107 4.5E-11
Hamap MF_00297 NAD-capped RNA hydrolase NudC [nudC]. IPR022925 NAD-capped RNA hydrolase NudC 8 273 50.643753
SUPERFAMILY SSF55811 Nudix IPR015797 NUDIX hydrolase-like domain superfamily 8 112 2.23E-23
PANTHER PTHR42904 NUDIX HYDROLASE, NUDC SUBFAMILY - - 79 266 8.5E-59
Pfam PF00293 NUDIX domain IPR000086 NUDIX hydrolase domain 145 258 4.0E-22
CDD cd03429 NADH_pyrophosphatase - - 145 267 8.29337E-52
Gene3D G3DSA:3.90.79.20 - - - 5 141 9.8E-27
Gene3D G3DSA:3.90.79.10 Nucleoside Triphosphate Pyrophosphohydrolase - - 142 270 2.8E-42
SUPERFAMILY SSF55811 Nudix IPR015797 NUDIX hydrolase-like domain superfamily 94 260 1.33E-45
FunFam G3DSA:3.90.79.20:FF:000004 NADH pyrophosphatase - - 5 141 1.8E-98
FunFam G3DSA:3.90.79.10:FF:000004 NADH pyrophosphatase - - 142 273 7.6E-59

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.