Pseudomonas aeruginosa PAO1, PA2057 (sppR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2057
Name
sppR
Replicon chromosome
Genomic location 2251275 - 2253815 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250747.1
GI 15597253
Affymetrix PA2057_at
Entrez 878519
GenBank AAG05445.1
INSDC AAG05445.1
NCBI Locus Tag PA2057
protein_id(GenBank) gb|AAG05445.1|AE004632_4|gnl|PseudoCAP|PA2057
TIGR NTL03PA02057
UniParc UPI00000C557A
UniProtKB Acc Q9I258
UniProtKB ID Q9I258_PSEAE
UniRef100 UniRef100_Q9I258
UniRef50 UniRef50_Q9I258
UniRef90 UniRef90_Q9I258

Product

Feature Type CDS
Coding Frame 1
Product Name
TonB-dependent receptor, SppR
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -13.00
Kyte-Doolittle Hydrophobicity Value -0.648
Molecular Weight (kDa) 93.7
Isoelectric Point (pI) 5.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 298 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003392 (315 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2057
Search term: sppR

Human Homologs

References

Swarming motility is modulated by expression of the putative xenosiderophore transporter SppR-SppABCD in Pseudomonas aeruginosa PA14.
Pletzer D, Braun Y, Weingart H
Antonie Van Leeuwenhoek 2016 Jun;109(6):737-53
PubMed ID: 26995781