Pseudomonas aeruginosa PAO1, PA2449 (gcsR)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0006546	glycine catabolic process	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	27303730	Reviewed by curator
Biological Process	GO:0045764	positive regulation of cellular amino acid metabolic process	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	23457254	Reviewed by curator
Biological Process	GO:1900378	positive regulation of secondary metabolite biosynthetic process	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	23457254	Reviewed by curator
Molecular Function	GO:0016791	phosphatase activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	27303730	Reviewed by curator
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA Inferred from Direct Assay	ECO:0000096 electrophoretic mobility shift assay evidence	27303730	Reviewed by curator
Biological Process	GO:0006521	regulation of cellular amino acid metabolic process	IMP Inferred from Mutant Phenotype
Molecular Function	GO:0008134	transcription factor binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00158	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003677	DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF18024	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00158	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016887	ATPase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00382	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006355	regulation of transcription, DNA-templated	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00158	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
FunFam	G3DSA:3.40.50.300:FF:000006	DNA-binding transcriptional regulator NtrC	-	-	194	373	4.6E-73
FunFam	G3DSA:1.10.8.60:FF:000136	Fis family transcriptional regulator	-	-	374	440	5.4E-48
Gene3D	G3DSA:3.40.50.300	-	IPR027417	P-loop containing nucleoside triphosphate hydrolase	191	373	7.0E-66
SUPERFAMILY	SSF46689	Homeodomain-like	IPR009057	Homeobox-like domain superfamily	456	508	2.45E-7
Gene3D	G3DSA:3.30.70.260	-	-	-	1	79	3.9E-17
CDD	cd00009	AAA	-	-	209	365	5.21165E-22
SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	IPR027417	P-loop containing nucleoside triphosphate hydrolase	203	445	1.69E-66
NCBIfam	TIGR04381	JCVI: TyrR family helix-turn-helix domain	IPR030828	TyrR family, helix-turn-helix domain	461	508	5.3E-24
SUPERFAMILY	SSF55785	PYP-like sensor domain (PAS domain)	IPR035965	PAS domain superfamily	80	130	3.29E-5
FunFam	G3DSA:1.10.10.60:FF:000489	Fis family transcriptional regulator	-	-	449	508	4.3E-43
Gene3D	G3DSA:1.10.10.60	-	-	-	449	508	1.0E-20
SMART	SM00382	AAA_5	IPR003593	AAA+ ATPase domain	222	367	2.0E-8
Pfam	PF00158	Sigma-54 interaction domain	IPR002078	RNA polymerase sigma factor 54 interaction domain	203	369	3.6E-64
Gene3D	G3DSA:3.30.450.20	PAS domain	-	-	81	186	3.5E-10
Gene3D	G3DSA:1.10.8.60	-	-	-	374	440	1.9E-20
PANTHER	PTHR32071	TRANSCRIPTIONAL REGULATORY PROTEIN	-	-	186	507	6.3E-114
Pfam	PF18024	Helix-turn-helix domain	IPR030828	TyrR family, helix-turn-helix domain	460	507	8.3E-14

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.