Pseudomonas aeruginosa PAO1, PA2987 (lolD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2987
Name
lolD
Synonym: ycfV
Replicon chromosome
Genomic location 3345113 - 3345796 (- strand)

Cross-References

RefSeq NP_251677.1
GI 15598183
Affymetrix PA2987_at
DNASU PaCD00007305
Entrez 880597
GenBank AAG06375.1
INSDC AAG06375.1
NCBI Locus Tag PA2987
protein_id(GenBank) gb|AAG06375.1|AE004724_4|gnl|PseudoCAP|PA2987
TIGR NTL03PA02987
UniParc UPI00000C58B8
UniProtKB Acc Q9HZL7
UniProtKB ID LOLD_PSEAE
UniRef100 UniRef100_Q9HZL7
UniRef50 UniRef50_Q9HZL7
UniRef90 UniRef90_Q9HZL7

Product

Feature Type CDS
Coding Frame 1
Product Name
lipoprotein localization protein LolD
Product Name Confidence: Class 1
Synonyms probable ATP-binding component of ABC transporter
Evidence for Translation
Charge (pH 7) -1.38
Kyte-Doolittle Hydrophobicity Value -0.059
Molecular Weight (kDa) 24.6
Isoelectric Point (pI) 6.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002595 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2987
Search term: lolD

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 2.5e-19
Percent Identity: 35.7
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 2.5e-19
Percent Identity: 35.7
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 2.5e-19
Percent Identity: 35.7

References

Characterization of the Pseudomonas aeruginosa Lol system as a lipoprotein sorting mechanism.
Tanaka SY, Narita S, Tokuda H
J Biol Chem 2007 May 4;282(18):13379-84
PubMed ID: 17350955