Pseudomonas aeruginosa PAO1, PA3175 (hutE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3175
Name
hutE
Replicon chromosome
Genomic location 3565189 - 3566124 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251865.1
GI 15598371
Affymetrix PA3175_at
Entrez 882685
GenBank AAG06563.1
INSDC AAG06563.1
NCBI Locus Tag PA3175
protein_id(GenBank) gb|AAG06563.1|AE004741_8|gnl|PseudoCAP|PA3175
TIGR NTL03PA03175
UniParc UPI00000C5937
UniProtKB Acc Q9HZ59
UniProtKB ID HUTG_PSEAE
UniRef100 UniRef100_Q9HZ59
UniRef50 UniRef50_Q4KJT9
UniRef90 UniRef90_Q9HZ59

Product

Feature Type CDS
Coding Frame 1
Product Name
HutE
Product Name Confidence: Class 1
Synonyms probable arginase family protein
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.29
Kyte-Doolittle Hydrophobicity Value -0.249
Molecular Weight (kDa) 34.2
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 264 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002440 (337 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3175
Search term: hutE
Search term: HutE

Human Homologs

References

The origin and ecological significance of multiple branches for histidine utilization in Pseudomonas aeruginosa PAO1.
Gerth ML, Ferla MP, Rainey PB
Environ Microbiol 2012 Aug;14(8):1929-40
PubMed ID: 22225844