Pseudomonas aeruginosa PAO1, PA3346 (hsbR)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0000156	phosphorelay response regulator activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	16182517	Reviewed by curator
Biological Process	GO:0000160	phosphorelay signal transduction system	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00072	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class Transcriptional regulators Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Two-component System		ECO:0000037 not_recorded
KEGG	pae02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae02025	Biofilm formation - Pseudomonas aeruginosa	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	413	570	2.7E-13
FunFam	G3DSA:3.40.50.2300:FF:000467	Probable two-component response regulator	-	-	11	176	4.6E-112
SMART	SM00331	PP2C_SIG_2	IPR001932	PPM-type phosphatase-like domain	186	386	1.2E-5
SMART	SM00448	REC_2	IPR001789	Signal transduction response regulator, receiver domain	11	124	4.2E-39
Gene3D	G3DSA:3.60.40.10	-	IPR036457	PPM-type phosphatase-like domain superfamily	177	391	8.7E-36
PANTHER	PTHR43156	STAGE II SPORULATION PROTEIN E-RELATED	-	-	175	388	1.4E-29
Pfam	PF07228	Stage II sporulation protein E (SpoIIE)	IPR001932	PPM-type phosphatase-like domain	198	386	7.4E-39
Pfam	PF13581	Histidine kinase-like ATPase domain	IPR003594	Histidine kinase/HSP90-like ATPase	489	563	1.9E-9
SUPERFAMILY	SSF52172	CheY-like	IPR011006	CheY-like superfamily	10	150	1.71E-38
CDD	cd16936	HATPase_RsbW-like	-	-	450	565	4.44403E-13
Gene3D	G3DSA:3.40.50.2300	-	-	-	11	176	2.5E-43
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	443	551	8.18E-7
Pfam	PF00072	Response regulator receiver domain	IPR001789	Signal transduction response regulator, receiver domain	13	124	1.9E-24

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.