Pseudomonas aeruginosa PAO1, PA4006 (nadD1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0051188 obsolete cofactor biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004515 nicotinate-nucleotide adenylyltransferase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 10894752 Reviewed by curator
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00125
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009058 biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00125
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009435 NAD biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00244
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016779 nucleotidyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00244
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Nicotinate and nicotinamide metabolism ECO:0000037
not_recorded
KEGG pae00760 Nicotinate and nicotinamide metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase 3 211 31.119993
NCBIfam TIGR00125 JCVI: cytidyltransferase-like domain IPR004821 Cytidyltransferase-like domain 5 68 5.2E-9
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 2 214 1.0E-74
FunFam G3DSA:3.40.50.620:FF:000291 Probable nicotinate-nucleotide adenylyltransferase - - 2 214 0.0
CDD cd02165 NMNAT IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase 5 210 2.93526E-80
PANTHER PTHR39321 NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE-RELATED IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase 1 211 7.7E-46
SUPERFAMILY SSF52374 Nucleotidylyl transferase - - 1 211 3.75E-53
NCBIfam TIGR00482 JCVI: nicotinate (nicotinamide) nucleotide adenylyltransferase IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase 7 210 3.8E-50
Pfam PF01467 Cytidylyltransferase-like IPR004821 Cytidyltransferase-like domain 7 184 7.4E-31

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.