Pseudomonas aeruginosa PAO1, PA4332 (sadC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0071978 bacterial-type flagellum-dependent swarming motility
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 17586642 Reviewed by curator
Biological Process GO:0044010 single-species biofilm formation
IMP
Inferred from Mutant Phenotype 		ECO:0000016
loss-of-function mutant phenotype evidence		 17586642 Reviewed by curator
Molecular Function GO:0005515 protein binding
EXP
Inferred from Experiment
Term mapped from: PseudoCAP:PA4379
 ECO:0007074
28263305 Reviewed by curator
Molecular Function GO:0052621 diguanylate cyclase activity
IDA
Inferred from Direct Assay 		ECO:0000005
enzyme assay evidence		 17586642 Reviewed by curator
Biological Process GO:1900192 positive regulation of single-species biofilm formation
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 26991003 Reviewed by curator

Functional Classifications Manually Assigned by PseudoCAP

Motility & Attachment Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Coils Coil Coil - - 305 325 -
Pfam PF00990 Diguanylate cyclase, GGDEF domain IPR000160 GGDEF domain 324 477 7.4E-43
PANTHER PTHR45138 REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM - - 262 478 5.6E-66
SUPERFAMILY SSF55073 Nucleotide cyclase IPR029787 Nucleotide cyclase 328 478 7.77E-46
FunFam G3DSA:3.30.70.270:FF:000001 Diguanylate cyclase domain protein - - 318 481 5.2E-50
Gene3D G3DSA:3.30.70.270 - IPR043128 Reverse transcriptase/Diguanylate cyclase domain 323 487 2.0E-57
CDD cd01949 GGDEF IPR000160 GGDEF domain 325 478 1.91612E-63
MobiDBLite mobidb-lite consensus disorder prediction - - 27 83 -
SMART SM00267 duf1_3 IPR000160 GGDEF domain 312 481 8.3E-59
NCBIfam TIGR00254 JCVI: diguanylate cyclase (GGDEF) domain IPR000160 GGDEF domain 319 479 3.3E-41

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.