Pseudomonas aeruginosa PAO1, PA4497 (dppA2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4497
Name
dppA2
Replicon chromosome
Genomic location 5033194 - 5034792 (+ strand)
Transposon Mutants 7 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253187.1
GI 15599693
Affymetrix PA4497_at
Entrez 881082
GenBank AAG07885.1
INSDC AAG07885.1
NCBI Locus Tag PA4497
protein_id(GenBank) gb|AAG07885.1|AE004863_5|gnl|PseudoCAP|PA4497
TIGR NTL03PA04498
UniParc UPI00000C5D39
UniProtKB Acc Q9HVS4
UniProtKB ID Q9HVS4_PSEAE
UniRef100 UniRef100_Q9HVS4
UniRef50 UniRef50_Q87WI5
UniRef90 UniRef90_V6ALA8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable binding protein component of ABC transporter
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.02
Kyte-Doolittle Hydrophobicity Value -0.378
Molecular Weight (kDa) 59.5
Isoelectric Point (pI) 7.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 557 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004085 (304 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4497
Search term: dppA2

Human Homologs

References

High-throughput screening of dipeptide utilization mediated by the ABC transporter DppBCDF and its substrate-binding proteins DppA1-A5 in Pseudomonas aeruginosa.
Pletzer D, Lafon C, Braun Y, Köhler T, Page MG, Mourez M, Weingart H
PLoS One 2014;9(10):e111311
PubMed ID: 25338022