Pseudomonas aeruginosa PAO1, PA4669 (ipk)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0050515 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 21282208 Reviewed by curator
Biological Process GO:0008299 isoprenoid biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 21282208 Reviewed by curator
Molecular Function GO:0050515 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF010376
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00288
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016114 terpenoid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF010376
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00900 Terpenoid backbone biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Terpenoid biosynthesis ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF010376 IspE IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase 3 279 4.5E-87
SUPERFAMILY SSF55060 GHMP Kinase, C-terminal domain IPR036554 GHMP kinase, C-terminal domain superfamily 160 277 2.73E-33
Gene3D G3DSA:3.30.230.10 - IPR014721 Small ribosomal subunit protein uS5 domain 2-type fold, subgroup 1 160 4.2E-59
NCBIfam TIGR00154 JCVI: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase 4 278 2.4E-83
PANTHER PTHR43527 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLOROPLASTIC - - 3 262 1.8E-71
FunFam G3DSA:3.30.230.10:FF:000022 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase - - 1 160 2.6E-79
Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase 5 271 33.124512
SUPERFAMILY SSF54211 Ribosomal protein S5 domain 2-like IPR020568 Ribosomal protein uS5 domain 2-type superfamily 7 158 1.97E-47
Pfam PF00288 GHMP kinases N terminal domain IPR006204 GHMP kinase N-terminal domain 87 144 1.6E-10
Gene3D G3DSA:3.30.70.890 - IPR036554 GHMP kinase, C-terminal domain superfamily 162 279 2.9E-30
Pfam PF08544 GHMP kinases C terminal IPR013750 GHMP kinase, C-terminal domain 205 254 2.5E-5

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.