Pseudomonas aeruginosa PAO1, PA4915

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4915
Name
Replicon chromosome
Genomic location 5514727 - 5516352 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253602.1
GI 15600108
Affymetrix PA4915_at
Entrez 879726
GenBank AAG08300.1
INSDC AAG08300.1
NCBI Locus Tag PA4915
protein_id(GenBank) gb|AAG08300.1|AE004904_8|gnl|PseudoCAP|PA4915
TIGR NTL03PA04916
UniParc UPI00000C5E79
UniProtKB Acc Q9HUP8
UniProtKB ID Q9HUP8_PSEAE
UniRef100 UniRef100_Q9HUP8
UniRef50 UniRef50_Q9HUP8
UniRef90 UniRef90_Q9HUP8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable chemotaxis transducer
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -12.80
Kyte-Doolittle Hydrophobicity Value 0.010
Molecular Weight (kDa) 57.9
Isoelectric Point (pI) 4.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Outer Membrane Class 2
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 398 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004533 (295 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4915

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Molecular cloning and characterization of a chemotactic transducer gene in Pseudomonas aeruginosa.
Kuroda A, Kumano T, Taguchi K, Nikata T, Kato J, Ohtake H
J Bacteriol 1995 Dec;177(24):7019-25
PubMed ID: 8522505
Genetic identification of chemotactic transducers for amino acids in Pseudomonas aeruginosa.
Taguchi K, Fukutomi H, Kuroda A, Kato J, Ohtake H
Microbiology (Reading) 1997 Oct;143 ( Pt 10):3223-3229
PubMed ID: 9353923