Pseudomonas aeruginosa PAO1, PA5147 (mutY)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016787 hydrolase activity
IGI
Inferred from Genetic Interaction 		ECO:0000316
genetic interaction evidence used in manual assertion		 12445642 Reviewed by curator
Biological Process GO:0006281 DNA repair
IGI
Inferred from Genetic Interaction 		ECO:0000316
genetic interaction evidence used in manual assertion		 12445642 Reviewed by curator
Biological Process GO:0006281 DNA repair
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 12445642 Reviewed by curator
Molecular Function GO:0016787 hydrolase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 12445642 Reviewed by curator
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00633
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006284 base-excision repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR42944
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016798 hydrolase activity, acting on glycosyl bonds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR42944
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0019104 DNA N-glycosylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01084
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48150
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48150
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd03431 DNA_Glycosylase_C IPR029119 Adenine DNA glycosylase, C-terminal 241 345 7.92256E-17
Gene3D G3DSA:3.90.79.10 Nucleoside Triphosphate Pyrophosphohydrolase - - 225 351 6.7E-16
SMART SM00478 endo3end IPR003265 HhH-GPD domain 39 190 8.4E-50
Pfam PF00633 Helix-hairpin-helix motif IPR000445 Helix-hairpin-helix motif 99 127 1.8E-8
Pfam PF14815 NUDIX domain IPR029119 Adenine DNA glycosylase, C-terminal 237 343 6.6E-22
FunFam G3DSA:1.10.340.30:FF:000002 Adenine DNA glycosylase - - 21 135 7.9E-49
Gene3D G3DSA:1.10.1670.10 - IPR023170 Helix-hairpin-helix, base-excision DNA repair, C-terminal 10 210 7.9E-87
SUPERFAMILY SSF55811 Nudix IPR015797 NUDIX hydrolase-like domain superfamily 220 345 5.19E-24
SUPERFAMILY SSF48150 DNA-glycosylase IPR011257 DNA glycosylase 4 224 9.11E-75
CDD cd00056 ENDO3c IPR003265 HhH-GPD domain 31 188 1.25946E-42
PANTHER PTHR42944 ADENINE DNA GLYCOSYLASE IPR044298 Adenine/Thymine-DNA glycosylase 6 347 3.6E-101
NCBIfam TIGR01084 JCVI: A/G-specific adenine glycosylase IPR005760 A/G-specific adenine glycosylase MutY 6 277 2.0E-109
Gene3D G3DSA:1.10.340.30 Hypothetical protein; domain 2 - - 21 132 7.9E-87
Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein IPR003265 HhH-GPD domain 35 168 1.2E-20

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.