Pseudomonas aeruginosa PAO1, PA0001 (dnaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003677 DNA binding
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 7615570 Reviewed by curator
Molecular Function GO:0043565 sequence-specific DNA binding
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 10551881 Reviewed by curator
Molecular Function GO:0003688 DNA replication origin binding
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 19833870 Reviewed by curator
Biological Process GO:0006260 DNA replication
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 12068813 Reviewed by curator
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd06571
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006270 DNA replication initiation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006275 regulation of DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003688 DNA replication origin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 244 258 1.8E-52
Pfam PF00308 Bacterial dnaA protein IPR013317 Chromosomal replication initiator protein DnaA 179 396 1.0E-99
FunFam G3DSA:3.40.50.300:FF:000103 Chromosomal replication initiator protein DnaA - - 177 344 4.8E-100
FunFam G3DSA:1.10.8.60:FF:000003 Chromosomal replication initiator protein DnaA - - 345 415 2.4E-33
Gene3D G3DSA:1.10.1750.10 - IPR010921 Trp repressor/replication initiator 421 514 4.0E-34
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 178 344 1.2E-49
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 472 491 1.8E-52
Pfam PF11638 DnaA N-terminal domain IPR024633 DnaA N-terminal domain 4 63 2.7E-20
Pfam PF08299 Bacterial dnaA protein helix-turn-helix IPR013159 Chromosomal replication initiator, DnaA C-terminal 423 491 1.8E-31
Gene3D G3DSA:1.10.8.60 - - - 345 415 6.2E-27
CDD cd06571 Bac_DnaA_C IPR013159 Chromosomal replication initiator, DnaA C-terminal 423 512 6.34824E-42
Gene3D G3DSA:3.30.300.180 - IPR038454 DnaA, N-terminal domain superfamily 2 102 1.3E-26
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 212 232 1.8E-52
PANTHER PTHR30050 CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA - - 1 504 0.0
FunFam G3DSA:1.10.1750.10:FF:000001 Chromosomal replication initiator protein DnaA - - 421 514 1.4E-54
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 211 420 2.3E-7
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 276 290 1.8E-52
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 310 337 1.8E-52
FunFam G3DSA:3.30.300.180:FF:000001 Chromosomal replication initiator protein DnaA - - 2 109 7.0E-41
Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. IPR001957 Chromosomal replication control, initiator DnaA 3 513 34.157234
CDD cd00009 AAA - - 212 337 6.18022E-18
SMART SM00760 bac_dnaa_c7seqb IPR013159 Chromosomal replication initiator, DnaA C-terminal 422 491 9.1E-44
NCBIfam TIGR00362 JCVI: chromosomal replication initiator protein DnaA IPR001957 Chromosomal replication control, initiator DnaA 6 512 0.0
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 180 390 2.21E-44
SUPERFAMILY SSF48295 TrpR-like IPR010921 Trp repressor/replication initiator 410 512 6.28E-37

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.