Pseudomonas aeruginosa PAO1, PA0016 (trkA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0016
Name
trkA
Replicon chromosome
Genomic location 17366 - 18739 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248706.1
GI 15595214
Affymetrix PA0016_trkA_at
Entrez 879255
GenBank AAG03406.1
INSDC AAG03406.1
NCBI Locus Tag PA0016
protein_id(GenBank) gb|AAG03406.1|AE004441_7|gnl|PseudoCAP|PA0016
TIGR NTL03PA00017
UniParc UPI00000C4EEB
UniProtKB Acc Q9I7B0
UniProtKB ID Q9I7B0_PSEAE
UniRef100 UniRef100_W0YJF0
UniRef50 UniRef50_E1V6C6
UniRef90 UniRef90_A6UX78

Product

Feature Type CDS
Coding Frame 1
Product Name
potassium uptake protein TrkA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -12.63
Kyte-Doolittle Hydrophobicity Value -0.042
Molecular Weight (kDa) 49.9
Isoelectric Point (pI) 5.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 417 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000016 (503 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0016
Search term: trkA

Human Homologs

References

Cloning and sequencing of a K+ transport gene (trk A) from the marine bacterium Vibrio alginolyticus.
Nakamura T, Matsuba Y, Yamamuro N, Booth IR, Unemoto T
Biochim Biophys Acta 1994 Nov 22;1219(3):701-5
PubMed ID: 7948029