Pseudomonas aeruginosa PAO1, PA0018 (fmt)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	6989606	Reviewed by curator
Molecular Function	GO:0004479	methionyl-tRNA formyltransferase activity	ISS Inferred from Sequence or Structural Similarity Term mapped from: UniProtKB:P23882	ECO:0000250 sequence similarity evidence used in manual assertion	6989606	Reviewed by curator
Biological Process	GO:0022898	regulation of transmembrane transporter activity	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	19786597	Reviewed by curator
Biological Process	GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00460	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0009058	biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF53328	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003824	catalytic activity	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF50486	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0004479	methionyl-tRNA formyltransferase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00460	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other PAO1 genes in this class Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Aminoacyl-tRNA biosynthesis		ECO:0000037 not_recorded
PseudoCAP		One carbon pool by folate		ECO:0000037 not_recorded
KEGG	pae00670	One carbon pool by folate	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00970	Aminoacyl-tRNA biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Methionine metabolism		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PANTHER	PTHR11138	METHIONYL-TRNA FORMYLTRANSFERASE	-	-	2	307	1.9E-81
Hamap	MF_00182	Methionyl-tRNA formyltransferase [fmt].	IPR005794	Methionyl-tRNA formyltransferase	5	305	37.065865
FunFam	G3DSA:3.40.50.170:FF:000003	Methionyl-tRNA formyltransferase	-	-	1	209	1.1E-109
SUPERFAMILY	SSF50486	FMT C-terminal domain-like	IPR011034	Formyl transferase-like, C-terminal domain superfamily	208	307	4.51E-31
Pfam	PF02911	Formyl transferase, C-terminal domain	IPR005793	Formyl transferase, C-terminal	207	302	1.2E-25
FunFam	G3DSA:3.10.25.10:FF:000009	Methionyl-tRNA formyltransferase	-	-	210	312	4.6E-68
FunFam	G3DSA:3.40.50.12230:FF:000001	Methionyl-tRNA formyltransferase	-	-	5	309	1.8E-111
Pfam	PF00551	Formyl transferase	IPR002376	Formyl transferase, N-terminal	6	184	7.3E-47
SUPERFAMILY	SSF53328	Formyltransferase	IPR036477	Formyl transferase, N-terminal domain superfamily	5	210	7.72E-67
Gene3D	G3DSA:3.40.50.170	-	-	-	1	209	4.4E-76
NCBIfam	TIGR00460	JCVI: methionyl-tRNA formyltransferase	IPR005794	Methionyl-tRNA formyltransferase	5	306	1.9E-94
CDD	cd08704	Met_tRNA_FMT_C	IPR044135	Methionyl-tRNA formyltransferase, C-terminal domain	211	294	7.32513E-35
CDD	cd08646	FMT_core_Met-tRNA-FMT_N	IPR041711	Methionyl-tRNA formyltransferase, N-terminal domain	5	208	1.04092E-111
Gene3D	G3DSA:3.10.25.10	-	IPR037022	Formyl transferase, C-terminal domain superfamily	210	312	4.6E-32

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.