Pseudomonas aeruginosa UCBPP-PA14, PA14_02590 (mdcE)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_02590
Name	mdcE
Replicon	chromosome
Genomic location	231082 - 231888 (+ strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_788363.1
GI	116053925
Entrez	4383604
INSDC	ABJ15161.1
NCBI Locus Tag	PA14_02590
UniParc	UPI0000396C94
UniProtKB Acc	Q02UM3
UniProtKB ID	Q02UM3_PSEAB
UniRef100	UniRef100_Q02UM3
UniRef50	UniRef50_W0V3F6
UniRef90	UniRef90_Q9I6S6

Product

Feature Type	CDS
Coding Frame	1
Product Name	malonate decarboxylase subunit gamma
Synonyms
Evidence for Translation
Charge (pH 7)	-0.83
Kyte-Doolittle Hydrophobicity Value	0.039
Molecular Weight (kDa)	28.5
Isoelectric Point (pI)	6.69

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
5VIP	TRANSFERASE	04/17/17	Crystal structure of Pseudomonas malonate decarboxylase MdcD-MdcE hetero-dimer	Pseudomonas aeruginosa	1.857	X-RAY DIFFRACTION	99.3
5VIT	TRANSFERASE	04/17/17	Crystal structure of a Pseudomonas malonate decarboxylase hetero-tetramer in complex with malonate	Pseudomonas aeruginosa; Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)	2.203	X-RAY DIFFRACTION	99.3
5VJ1	TRANSFERASE	04/18/17	Crystal structure of a Pseudomonas malonate decarboxylase hetero-tetramer in complex with coenzyme A	Pseudomonas aeruginosa; Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)	2.995	X-RAY DIFFRACTION	99.3

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 57 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000211 (478 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_02590 Search term: mdcE Search term: malonate decarboxylase subunit gamma

Human Homologs

References