Pseudomonas aeruginosa UCBPP-PA14, PA14_09710

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_09710
Name
Replicon	chromosome
Genomic location	835206 - 836696 (- strand)
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_788925.1
GI	116052231
Entrez	4382204
INSDC	ABJ13467.1
NCBI Locus Tag	PA14_09710
UniParc	UPI00000C5C62
UniProtKB Acc	Q02T11
UniProtKB ID	Q02T11_PSEAB
UniRef100	UniRef100_W0YYM9
UniRef50	UniRef50_A0A085H6C2
UniRef90	UniRef90_V6A9V5

Product

Feature Type	CDS
Coding Frame	1
Product Name	aldehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-13.53
Kyte-Doolittle Hydrophobicity Value	-0.006
Molecular Weight (kDa)	53.4
Isoelectric Point (pI)	5.07

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
7UYY	OXIDOREDUCTASE	05/07/22	The crystal structure of the Pseudomonas aeruginosa aldehyde dehydrogenase encoded by the PA4189 gene in complex with NADH	Pseudomonas aeruginosa PAO1	2.7	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 601 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001512 (334 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_09710 Search term: aldehyde dehydrogenase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000499136 aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777] E-value: 1.6e-98 Percent Identity: 39.9
Ensembl 110, assembly GRCh38.p14	ENSP00000258494 aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777] E-value: 1.6e-98 Percent Identity: 39.9
Ensembl 110, assembly GRCh38.p14	ENSP00000297785 aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402] E-value: 1.6e-98 Percent Identity: 41.2

References