Pseudomonas aeruginosa UCBPP-PA14, PA14_37840 (sppD)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_37840
Name	sppD
Replicon	chromosome
Genomic location	3374868 - 3376478 (- strand)
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_791177.1
GI	116050010
Entrez	4382351
INSDC	ABJ11246.1
NCBI Locus Tag	PA14_37840
UniParc	UPI000039697C
UniProtKB Acc	Q02LK9
UniProtKB ID	Q02LK9_PSEAB
UniRef100	UniRef100_S0I8Y5
UniRef50	UniRef50_P33916
UniRef90	UniRef90_Q9I254

Product

Feature Type	CDS
Coding Frame	1
Product Name	ABC transporter ATP-binding protein, SppD Product Name Confidence: Class 1
Synonyms	ABC transporter ATP-binding protein
Evidence for Translation
Charge (pH 7)	17.42
Kyte-Doolittle Hydrophobicity Value	-0.080
Molecular Weight (kDa)	59.3
Isoelectric Point (pI)	10.20

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003388 (296 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_37840 Search term: sppD Search term: ABC transporter ATP-binding protein, SppD

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000355637 ATP binding cassette subfamily B member 10 [Source:HGNC Symbol;Acc:HGNC:41] E-value: 6.4e-21 Percent Identity: 31.3

References

Swarming motility is modulated by expression of the putative xenosiderophore transporter SppR-SppABCD in Pseudomonas aeruginosa PA14. Pletzer D, Braun Y, Weingart H Antonie Van Leeuwenhoek 2016 Jun;109(6):737-53 PubMed ID: 26995781