Pseudomonas aeruginosa UCBPP-PA14, PA14_37880 (sppA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_37880
Name
sppA
Replicon chromosome
Genomic location 3378573 - 3380381 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq YP_791180.1
GI 116050007
Entrez 4382348
INSDC ABJ11243.1
NCBI Locus Tag PA14_37880
UniParc UPI0000396979
UniProtKB Acc Q02LK6
UniProtKB ID Q02LK6_PSEAB
UniRef100 UniRef100_S0IQ22
UniRef50 UniRef50_A0A0D0RCL5
UniRef90 UniRef90_W0YQ03

Product

Feature Type CDS
Coding Frame 1
Product Name
ABC transporter substrate-binding protein, SppA
Product Name Confidence: Class 1
Synonyms ABC transporter substrate-binding protein
Evidence for Translation
Charge (pH 7) 4.89
Kyte-Doolittle Hydrophobicity Value -0.492
Molecular Weight (kDa) 69.2
Isoelectric Point (pI) 8.70

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 340 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003391 (817 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_37880
Search term: sppA

Human Homologs

References

Swarming motility is modulated by expression of the putative xenosiderophore transporter SppR-SppABCD in Pseudomonas aeruginosa PA14.
Pletzer D, Braun Y, Weingart H
Antonie Van Leeuwenhoek 2016 Jun;109(6):737-53
PubMed ID: 26995781