Pseudomonas aeruginosa UCBPP-PA14, PA14_70330 (sphC)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
| Locus Tag |
PA14_70330
|
| Name |
sphC
|
| Replicon | chromosome |
| Genomic location | 6271267 - 6272595 (- strand) |
| Transposon Mutants | 1 transposon mutants in UCBPP-PA14 |
| Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Cross-References
| RefSeq | YP_793801.1 |
| GI | 116053474 |
| Entrez | 4385090 |
| NCBI Locus Tag | PA14_70330 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
SphC
|
| Synonyms |
oxidoreductase |
| Evidence for Translation | |
| Charge (pH 7) | -2.50 |
| Kyte-Doolittle Hydrophobicity Value | -0.282 |
| Molecular Weight (kDa) | 49.4 |
| Isoelectric Point (pI) | 6.68 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 128 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG004896 (350 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_70330
Search term: sphC
Search term: SphC
|
Human Homologs
References
|
Detection of host-derived sphingosine by Pseudomonas aeruginosa is important for survival in the murine lung.
LaBauve AE, Wargo MJ
PLoS Pathog 2014 Jan;10(1):e1003889
PubMed ID: 24465209
|