Pseudomonas aeruginosa UCBPP-PA14, PA14_70340 (sphB)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_70340
Name	sphB
Replicon	chromosome
Genomic location	6272673 - 6273062 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	6 transposon mutants in orthologs

Cross-References

RefSeq	YP_793802.1
GI	116053475
Entrez	4385091
INSDC	ABJ14711.1
NCBI Locus Tag	PA14_70340
UniParc	UPI0000E44C7F
UniProtKB Acc	Q02E34
UniProtKB ID	Q02E34_PSEAB
UniRef100	UniRef100_V6AP77
UniRef50	UniRef50_Q4KAC1
UniRef90	UniRef90_Q9HTM7

Product

Feature Type	CDS
Coding Frame	1
Product Name	SphB Product Name Confidence: Class 1
Synonyms	cytochrome c(mono-heme type)
Evidence for Translation
Charge (pH 7)	-1.72
Kyte-Doolittle Hydrophobicity Value	-0.070
Molecular Weight (kDa)	13.5
Isoelectric Point (pI)	5.65

Subcellular localization

Individual Mappings	Localization Confidence PMID Periplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 96 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004897 (786 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_70340 Search term: sphB Search term: SphB

Human Homologs

References

Detection of host-derived sphingosine by Pseudomonas aeruginosa is important for survival in the murine lung. LaBauve AE, Wargo MJ PLoS Pathog 2014 Jan;10(1):e1003889 PubMed ID: 24465209