Pseudomonas entomophila L48, PSEEN0132 (pvfC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas entomophila L48
GCF_000026105.1|latest
Locus Tag
PSEEN0132
Name
pvfC
Replicon chromosome
Genomic location 121613 - 125044 (- strand)

Cross-References

RefSeq YP_605926.1
GI 104779428
Entrez 4087801
INSDC CAK13109.1
UniParc UPI0000D77F0A
UniProtKB Acc Q1IGU3
UniProtKB ID Q1IGU3_PSEE4
UniRef100 UniRef100_Q1IGU3
UniRef50 UniRef50_D7I6L3
UniRef90 UniRef90_Q1IGU3

Product

Feature Type CDS
Coding Frame 1
Product Name
PvfC
Product Name Confidence: Class 1
Synonyms non ribosomal peptide synthethase, loading module
Evidence for Translation
Charge (pH 7) -15.43
Kyte-Doolittle Hydrophobicity Value -0.166
Molecular Weight (kDa) 126749.0
Isoelectric Point (pI) 6.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 549 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG018985 (62 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSEEN0132
Search term: pvfC
Search term: PvfC

Human Homologs

Ensembl 110, assembly GRCh38.p14
acyl-CoA synthetase long chain family member 6 [Source:HGNC Symbol;Acc:HGNC:16496]
E-value: 3.4e-11
Percent Identity: 24.6
Ensembl 110, assembly GRCh38.p14
acyl-CoA synthetase long chain family member 6 [Source:HGNC Symbol;Acc:HGNC:16496]
E-value: 3.4e-11
Percent Identity: 24.6

References

A secondary metabolite acting as a signalling molecule controls Pseudomonas entomophila virulence.
Vallet-Gely I, Opota O, Boniface A, Novikov A, Lemaitre B
Cell Microbiol 2010 Nov;12(11):1666-79
PubMed ID: 20597908