Pseudomonas aeruginosa UCBPP-PA14, PA14_61845 (higB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_61845
Name
higB
Replicon chromosome
Genomic location 5514513 - 5514791 (- strand)

Cross-References

RefSeq
GI

Product

Feature Type CDS
Coding Frame 1
Product Name
HigB
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 1.65
Kyte-Doolittle Hydrophobicity Value -0.421
Molecular Weight (kDa) 10.6
Isoelectric Point (pI) 8.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_61845
Search term: higB
Search term: HigB

Human Homologs

References

The HigB/HigA toxin/antitoxin system of Pseudomonas aeruginosa influences the virulence factors pyochelin, pyocyanin, and biofilm formation.
Wood TL, Wood TK
Microbiologyopen 2016 Jun;5(3):499-511
PubMed ID: 26987441