Pseudomonas aeruginosa PAO1, PA0114 (senC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0114
Name
senC
Replicon chromosome
Genomic location 135259 - 135894 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_248804.1
GI 15595312
Affymetrix PA0114_at
DNASU PaCD00006049
Entrez 879388
GenBank AAG03504.1
INSDC AAG03504.1
NCBI Locus Tag PA0114
protein_id(GenBank) gb|AAG03504.1|AE004449_13|gnl|PseudoCAP|PA0114
TIGR NTL03PA00115
UniParc UPI00000C4F43
UniProtKB Acc Q9I718
UniProtKB ID Q9I718_PSEAE
UniRef100 UniRef100_W0YM44
UniRef50 UniRef50_Q4KKL1
UniRef90 UniRef90_K1DT36

Product

Feature Type CDS
Coding Frame 1
Product Name
SenC
Product Name Confidence: Class 1
Evidence for Translation
Detected using LC-MS/MS (23.02 kDa, PMID:21751344)
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.89
Kyte-Doolittle Hydrophobicity Value -0.018
Molecular Weight (kDa) 23.0
Isoelectric Point (pI) 8.22

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Outer Membrane Vesicle Class 1
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 276 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000112 (555 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0114
Search term: senC
Search term: SenC

Transposon Insertions in PAO1

Type ISphoA/hah insertion site
Mutant ID UWGC: 33108
Genomic Position 135325
Position in ORF 67(636)
Reference 14617778
Type ISphoA/hah insertion site
Mutant ID UWGC: 30535
Genomic Position 135613
Position in ORF 355(636)
Reference 14617778

Transposon Insertions in Orthologs

References

Copper acquisition by the SenC protein regulates aerobic respiration in Pseudomonas aeruginosa PAO1.
Frangipani E, Haas D
FEMS Microbiol. Lett. 2009 Sep;298(2):234-40
PubMed ID: 19659575
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344