Pseudomonas aeruginosa PAO1, PA0180 (cttP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0180
Name
cttP
Synonym: mcpA
Replicon chromosome
Genomic location 204657 - 205829 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_248870.1
GI 15595378
Affymetrix PA0180_at
Entrez 879336
GenBank AAG03570.1
INSDC AAG03570.1
NCBI Locus Tag PA0180
protein_id(GenBank) gb|AAG03570.1|AE004456_1|gnl|PseudoCAP|PA0180
TIGR NTL03PA00181
UniParc UPI00000C4F82
UniProtKB Acc Q9I6V2
UniProtKB ID Q9I6V2_PSEAE
UniRef100 UniRef100_W0YK52
UniRef50 UniRef50_K1EJU5
UniRef90 UniRef90_K1EJU5

Product

Feature Type CDS
Coding Frame 1
Product Name
chemotactic transducer for trichloroethylene [positive chemotaxis], CttP
Product Name Confidence: Class 1
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.88
Kyte-Doolittle Hydrophobicity Value -0.119
Molecular Weight (kDa) 42.8
Isoelectric Point (pI) 5.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 394 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000178 (402 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0180
Search term: cttP

Transposon Insertions in PAO1

Type Confirmed ISphoA/hah insertion site
Mutant ID UWGC: 53755
Genomic Position 204791
Position in ORF 135(1173)
Reference 14617778
Type Confirmed ISphoA/hah insertion site
Mutant ID UWGC: 47274
Genomic Position 205352
Position in ORF 696(1173)
Reference 14617778

Transposon Insertions in Orthologs

References

A signal transducer for aerotaxis in Escherichia coli.
Bibikov SI, Biran R, Rudd KE, Parkinson JS.
J Bacteriol. 1997 Jun;179(12):4075-9.
PubMed ID: 9190831
Identification and characterization of the chemotactic transducer in Pseudomonas aeruginosa PAO1 for positive chemotaxis to trichloroethylene.
Kim HE, Shitashiro M, Kuroda A, Takiguchi N, Ohtake H, Kato J.
J Bacteriol. 2006 Sep;188(18):6700-2.
PubMed ID: 16952963