Pseudomonas aeruginosa PAO1, PA0197 (tonB2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0197
Name
tonB2
Replicon chromosome
Genomic location 227382 - 228194 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_248888.1
GI 15595394
Affymetrix PA0197_at
Entrez 879472
GenBank AAG03586.1
INSDC AAG03586.1
NCBI Locus Tag PA0197
protein_id(GenBank) gb|AAG03586.1|AE004458_1|gnl|PseudoCAP|PA0197
TIGR NTL03PA00198
UniParc UPI00000D4276
UniProtKB Acc Q9RMT3
UniProtKB ID TONB2_PSEAE
UniRef100 UniRef100_Q9RMT3
UniRef50 UniRef50_Q9RMT3
UniRef90 UniRef90_Q9RMT3

Product

Feature Type CDS
Coding Frame 1
Product Name
TonB2
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 9.44
Kyte-Doolittle Hydrophobicity Value -0.412
Molecular Weight (kDa) 28.8
Isoelectric Point (pI) 10.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 132 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000196 (474 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0197
Search term: tonB2
Search term: TonB2

Human Homologs

Ensembl 86, assembly GRCh38.p7
lysine acetyltransferase 6A [Source:HGNC Symbol;Acc:HGNC:13013]
E-value: 5.5e-08
Percent Identity: 36.3

Transposon Insertions in PAO1

Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 9243
Genomic Position 227997
Position in ORF 616(813)
Reference 14617778
Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 9243
Genomic Position 227997
Position in ORF 616(813)
Reference 14617778

Transposon Insertions in Orthologs

References

The Pseudomonas aeruginosa tonB gene encodes a novel TonB protein.
Poole K, Zhao Q, Neshat S, Heinrichs DE, Dean CR.
Microbiology. 1996 Jun;142 ( Pt 6):1449-58.
PubMed ID: 8704984
A second tonB gene in Pseudomonas aeruginosa is linked to the exbB and exbD genes.
Zhao Q, Poole K.
FEMS Microbiol Lett. 2000 Mar 1;184(1):127-32.
PubMed ID: 10689178