Pseudomonas aeruginosa PAO1, PA0210 (mdcC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0210
Name
mdcC
Replicon chromosome
Genomic location 239779 - 240078 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_248901.1
GI 15595407
Affymetrix PA0210_mdcC_at
DNASU PaCD00006097
Entrez 883035
GenBank AAG03599.1
INSDC AAG03599.1
NCBI Locus Tag PA0210
protein_id(GenBank) gb|AAG03599.1|AE004459_3|gnl|PseudoCAP|PA0210
TIGR NTL03PA00211
UniParc UPI00000C4F99
UniProtKB Acc Q9I6S8
UniProtKB ID MDCC_PSEAE
UniRef100 UniRef100_Q02UM5
UniRef50 UniRef50_A6UY05
UniRef90 UniRef90_Q02UM5

Product

Feature Type CDS
Coding Frame 1
Product Name
malonate decarboxylase delta subunit
Product Name Confidence: Class 2
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.56
Kyte-Doolittle Hydrophobicity Value 0.203
Molecular Weight (kDa) 10.2
Isoelectric Point (pI) 4.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 56 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000209 (506 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0210
Search term: mdcC

Transposon Insertions in PAO1

Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 9096
Genomic Position 239825
Position in ORF 47(300)
Reference 14617778

Transposon Insertions in Orthologs

References

Sequence of a gene cluster from Klebsiella pneumoniae encoding malonate decarboxylase and expression of the enzyme in Escherichia coli.
Hoenke S, Schmid M, Dimroth P.
Eur J Biochem. 1997 Jun 1;246(2):530-8.
PubMed ID: 9208947