Pseudomonas aeruginosa PAO1, PA0227

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0227
Name
Synonym: pcaJ
Replicon chromosome
Genomic location 256329 - 257111 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248918.1
GI 15595424
Affymetrix PA0227_at
DNASU PaCD00006102
Entrez 877818
GenBank AAG03616.1
INSDC AAG03616.1
NCBI Locus Tag PA0227
protein_id(GenBank) gb|AAG03616.1|AE004460_9|gnl|PseudoCAP|PA0227
TIGR NTL03PA00228
UniParc UPI00000C4FAA
UniProtKB Acc Q9I6R1
UniProtKB ID Q9I6R1_PSEAE
UniRef100 UniRef100_W0YL72
UniRef50 UniRef50_G8PXF6
UniRef90 UniRef90_A0A087L9D8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable CoA transferase, subunit B
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -4.86
Kyte-Doolittle Hydrophobicity Value -0.002
Molecular Weight (kDa) 27.3
Isoelectric Point (pI) 5.37

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 241 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000226 (497 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0227

Human Homologs

References

Glutaconate CoA-transferase from Acidaminococcus fermentans: the crystal structure reveals homology with other CoA-transferases.
Jacob U, Mack M, Clausen T, Huber R, Buckel W, Messerschmidt A
Structure 1997 Mar 15;5(3):415-26
PubMed ID: 9083111