Pseudomonas aeruginosa PAO1, PA0229 (pcaT)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0229
Name
pcaT
Synonym: kgtP
Replicon chromosome
Genomic location 258463 - 259761 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248920.1
GI 15595426
Affymetrix PA0229_pcaT_at
Entrez 878155
GenBank AAG03618.1
INSDC AAG03618.1
NCBI Locus Tag PA0229
protein_id(GenBank) gb|AAG03618.1|AE004461_1|gnl|PseudoCAP|PA0229
TIGR NTL03PA00230
UniParc UPI00000C4FAC
UniProtKB Acc Q9I6Q9
UniProtKB ID Q9I6Q9_PSEAE
UniRef100 UniRef100_W0YL03
UniRef50 UniRef50_P0AEX3
UniRef90 UniRef90_A6UY26

Product

Feature Type CDS
Coding Frame 1
Product Name
dicarboxylic acid transporter PcaT
Product Name Confidence: Class 2
Synonyms alpha-ketoglutarate permease
Evidence for Translation
Charge (pH 7) 10.52
Kyte-Doolittle Hydrophobicity Value 0.624
Molecular Weight (kDa) 47.2
Isoelectric Point (pI) 9.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 341 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000228 (485 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0229
Search term: pcaT

Human Homologs

References

Escherichia coli kgtP encodes an alpha-ketoglutarate transporter.
Seol W, Shatkin AJ
Proc Natl Acad Sci U S A 1991 May 1;88(9):3802-6
PubMed ID: 2053984