Pseudomonas aeruginosa PAO1, PA0245 (aroQ2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0245
Name
aroQ2
Synonym: aroD2
Replicon chromosome
Genomic location 277331 - 277777 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_248936.1
GI 15595442
Affymetrix PA0245_aroQ2_at
DNASU PaCD00006109
Entrez 882159
GenBank AAG03634.1
INSDC AAG03634.1
NCBI Locus Tag PA0245
protein_id(GenBank) gb|AAG03634.1|AE004462_7|gnl|PseudoCAP|PA0245
TIGR NTL03PA00246
UniParc UPI0000126073
UniProtKB Acc Q9I6P3
UniProtKB ID AROQ2_PSEAE
UniRef100 UniRef100_Q9I6P3
UniRef50 UniRef50_P15474
UniRef90 UniRef90_Q9I6P3

Product

Feature Type CDS
Coding Frame 1
Product Name
3-dehydroquinate dehydratase
Product Name Confidence: Class 2
Synonyms dehydroquinase
Evidence for Translation
Charge (pH 7) -0.39
Kyte-Doolittle Hydrophobicity Value 0.003
Molecular Weight (kDa) 16.3
Isoelectric Point (pI) 6.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 474 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000243 (462 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0245
Search term: aroQ2

Human Homologs

References

Characterization of a 3-dehydroquinase gene from Actinobacillus pleuropneumoniae with homology to the eukaryotic genes qa-2 and QUTE.
Lalonde G, O'Hanley PD, Stocker BA, Denich KT
Mol Microbiol 1994 Jan;11(2):273-80
PubMed ID: 8170389