Pseudomonas aeruginosa PAO1, PA0246

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0246
Name
Replicon chromosome
Genomic location 277894 - 279399 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248937.1
GI 15595443
Affymetrix PA0246_at
Entrez 881952
GenBank AAG03635.1
INSDC AAG03635.1
NCBI Locus Tag PA0246
protein_id(GenBank) gb|AAG03635.1|AE004462_8|gnl|PseudoCAP|PA0246
TIGR NTL03PA00247
UniParc UPI00000C4FBC
UniProtKB Acc Q9I6P2
UniProtKB ID Q9I6P2_PSEAE
UniRef100 UniRef100_Q9I6P2
UniRef50 UniRef50_Q4K783
UniRef90 UniRef90_Q9I6P2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 8.27
Kyte-Doolittle Hydrophobicity Value 0.897
Molecular Weight (kDa) 52.4
Isoelectric Point (pI) 9.31

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 585 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000244 (488 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0246

Human Homologs

References

bmr3, a third multidrug transporter gene of Bacillus subtilis.
Ohki R, Murata M
J Bacteriol 1997 Feb;179(4):1423-7
PubMed ID: 9023234