Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0265
|
Name |
davD
Synonym: gabD |
Replicon | chromosome |
Genomic location | 299522 - 300973 (+ strand) |
Transposon Mutants | 4 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_248956.1 |
GI | 15595462 |
Affymetrix | PA0265_gabD_at |
Entrez | 881913 |
GenBank | AAG03654.1 |
INSDC | AAG03654.1 |
NCBI Locus Tag | PA0265 |
protein_id(GenBank) | gb|AAG03654.1|AE004464_7|gnl|PseudoCAP|PA0265 |
TIGR | NTL03PA00266 |
UniParc | UPI00000C4FCD |
UniProtKB Acc | Q9I6M5 |
UniProtKB ID | DAVD_PSEAE |
UniRef100 | UniRef100_Q9I6M5 |
UniRef50 | UniRef50_P25526 |
UniRef90 | UniRef90_Q9I6M5 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
glutaric semialdehyde dehydrogenase
|
Synonyms |
succinate-semialdehyde dehydrogenase |
Evidence for Translation |
Detected by iTRAQ (PMID:21863142).
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -4.41 |
Kyte-Doolittle Hydrophobicity Value | -0.031 |
Molecular Weight (kDa) | 51.6 |
Isoelectric Point (pI) | 5.43 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 604 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000262 (536 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0265
Search term: davD
Search term: glutaric semialdehyde dehydrogenase
|
Ensembl
110, assembly
GRCh38.p14
|
aldehyde dehydrogenase 5 family member A1 [Source:HGNC Symbol;Acc:HGNC:408]
E-value:
2.3e-158
Percent Identity:
57.9
|
Isolation and properties of Escherichia coli K-12 mutants impaired in the utilization of gamma-aminobutyrate.
Metzer E, Levitz R, Halpern YS
J Bacteriol 1979 Mar;137(3):1111-8
PubMed ID: 374339
|
Molecular organization of the Escherichia coli gab cluster: nucleotide sequence of the structural genes gabD and gabP and expression of the GABA permease gene.
Niegemann E, Schulz A, Bartsch K
Arch Microbiol 1993;160(6):454-60
PubMed ID: 8297211
|
Functional characterization of seven γ-Glutamylpolyamine synthetase genes and the bauRABCD locus for polyamine and β-Alanine utilization in Pseudomonas aeruginosa PAO1.
Yao X, He W, Lu CD
J. Bacteriol. 2011 Aug;193(15):3923-30
PubMed ID: 21622750
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142
|
Multiple and interconnected pathways for L-lysine catabolism in Pseudomonas putida KT2440.
Revelles O, Espinosa-Urgel M, Fuhrer T, Sauer U, Ramos JL
J Bacteriol 2005 Nov;187(21):7500-10
PubMed ID: 16237033
|