Pseudomonas aeruginosa PAO1, PA0287 (gpuP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0287
Name
gpuP
Synonym: speB1
Replicon chromosome
Genomic location 322175 - 323560 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq NP_248978.1
GI 15595484
Affymetrix PA0287_at
Entrez 879633
GenBank AAG03676.1
INSDC AAG03676.1
NCBI Locus Tag PA0287
protein_id(GenBank) gb|AAG03676.1|AE004466_10|gnl|PseudoCAP|PA0287
TIGR NTL03PA00288
UniParc UPI00000C4FE3
UniProtKB Acc Q9I6K3
UniProtKB ID Q9I6K3_PSEAE
UniRef100 UniRef100_W0YJR6
UniRef50 UniRef50_Q4KJW2
UniRef90 UniRef90_W0YJR6

Product

Feature Type CDS
Coding Frame 1
Product Name
3-guanidinopropionate transport protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.98
Kyte-Doolittle Hydrophobicity Value 1.030
Molecular Weight (kDa) 48.5
Isoelectric Point (pI) 8.83

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 439 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000284 (771 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0287
Search term: gpuP

Human Homologs

References

Cloning, sequence, and expression of the pantothenate permease (panF) gene of Escherichia coli.
Jackowski S, Alix JH
J Bacteriol 1990 Jul;172(7):3842-8
PubMed ID: 2193919