Pseudomonas aeruginosa PAO1, PA0298 (spuB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0298
Name
spuB
Replicon chromosome
Genomic location 335527 - 336885 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248989.1
GI 15595495
Affymetrix PA0298_at
Entrez 880835
GenBank AAG03687.1
INSDC AAG03687.1
NCBI Locus Tag PA0298
protein_id(GenBank) gb|AAG03687.1|AE004467_9|gnl|PseudoCAP|PA0298
TIGR NTL03PA00299
UniParc UPI00000C4FED
UniProtKB Acc Q9I6J3
UniProtKB ID Q9I6J3_PSEAE
UniRef100 UniRef100_W0YKA1
UniRef50 UniRef50_A4XP49
UniRef90 UniRef90_A4XP49

Product

Feature Type CDS
Coding Frame 1
Product Name
Glutamylpolyamine synthetase
Product Name Confidence: Class 1
Synonyms pauA2
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -12.96
Kyte-Doolittle Hydrophobicity Value -0.301
Molecular Weight (kDa) 51.0
Isoelectric Point (pI) 5.01

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 579 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000295 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0298
Search term: spuB

Human Homologs

References

Functional characterization of seven γ-Glutamylpolyamine synthetase genes and the bauRABCD locus for polyamine and β-Alanine utilization in Pseudomonas aeruginosa PAO1.
Yao X, He W, Lu CD
J. Bacteriol. 2011 Aug;193(15):3923-30
PubMed ID: 21622750