Pseudomonas aeruginosa PAO1, PA0299 (spuC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0299
Name
spuC
Replicon chromosome
Genomic location 336951 - 338321 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248990.1
GI 15595496
Affymetrix PA0299_at
Entrez 878357
GenBank AAG03688.1
INSDC AAG03688.1
NCBI Locus Tag PA0299
protein_id(GenBank) gb|AAG03688.1|AE004467_10|gnl|PseudoCAP|PA0299
TIGR NTL03PA00300
UniParc UPI00000C4FEE
UniProtKB Acc Q9I6J2
UniProtKB ID Q9I6J2_PSEAE
UniRef100 UniRef100_W0YMM7
UniRef50 UniRef50_Q7NWG4
UniRef90 UniRef90_A0A024HQS0

Product

Feature Type CDS
Coding Frame 1
Product Name
Polyamine:pyruvate transaminase
Product Name Confidence: Class 2
Synonyms spuC
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.25
Kyte-Doolittle Hydrophobicity Value -0.148
Molecular Weight (kDa) 50.5
Isoelectric Point (pI) 5.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 639 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000296 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0299
Search term: spuC

Human Homologs

References

Functional analysis and regulation of the divergent spuABCDEFGH-spuI operons for polyamine uptake and utilization in Pseudomonas aeruginosa PAO1.
Lu CD, Itoh Y, Nakada Y, Jiang Y
J Bacteriol 2002 Jul;184(14):3765-73
PubMed ID: 12081945
Functional characterization of seven γ-Glutamylpolyamine synthetase genes and the bauRABCD locus for polyamine and β-Alanine utilization in Pseudomonas aeruginosa PAO1.
Yao X, He W, Lu CD
J. Bacteriol. 2011 Aug;193(15):3923-30
PubMed ID: 21622750