Pseudomonas aeruginosa PAO1, PA0364 (laoA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0364
Name
laoA
Replicon chromosome
Genomic location 407250 - 408845 (- strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentPart of the Lao (long-chain-alcohol/aldehyde-oxidation) gene cluster (laoABC).

Cross-References

RefSeq NP_249055.1
GI 15595561
Affymetrix PA0364_at
Entrez 879858
GenBank AAG03753.1
INSDC AAG03753.1
NCBI Locus Tag PA0364
protein_id(GenBank) gb|AAG03753.1|AE004474_5|gnl|PseudoCAP|PA0364
TIGR NTL03PA00365
UniParc UPI00000C5029
UniProtKB Acc Q9I6D0
UniProtKB ID Q9I6D0_PSEAE
UniRef100 UniRef100_S0JE53
UniRef50 UniRef50_W7W1R1
UniRef90 UniRef90_B7V2S7

Product

Feature Type CDS
Coding Frame 1
Product Name
LaoA
Product Name Confidence: Class 1
Synonyms probable oxidoreductase
Evidence for Translation
Charge (pH 7) -0.35
Kyte-Doolittle Hydrophobicity Value -0.201
Molecular Weight (kDa) 57.8
Isoelectric Point (pI) 6.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 163 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000355 (488 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0364
Search term: laoA
Search term: LaoA

Human Homologs

References

LaoABCR, a Novel System for Oxidation of Long-Chain Alcohols Derived from SDS and Alkane Degradation in Pseudomonas aeruginosa.
Panasia G, Philipp B
Appl Environ Microbiol 2018 Jul 1;84(13)
PubMed ID: 29678916