Pseudomonas aeruginosa PAO1, PA0390 (metX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0390
Name
metX
Synonym: met2
Replicon chromosome
Genomic location 430630 - 431769 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249081.1
GI 15595587
Affymetrix PA0390_metX_at
DNASU PaCD00006169
Entrez 878549
GenBank AAG03779.1
INSDC AAG03779.1
NCBI Locus Tag PA0390
protein_id(GenBank) gb|AAG03779.1|AE004476_9|gnl|PseudoCAP|PA0390
TIGR NTL03PA00391
UniParc UPI000012F019
UniProtKB Acc P57714
UniProtKB ID METX_PSEAE
UniRef100 UniRef100_Q02U23
UniRef50 UniRef50_Q9JZQ5
UniRef90 UniRef90_Q02U23

Product

Feature Type CDS
Coding Frame 1
Product Name
homoserine O-acetyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.30
Kyte-Doolittle Hydrophobicity Value -0.140
Molecular Weight (kDa) 41.8
Isoelectric Point (pI) 5.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 370 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000381 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0390
Search term: metX

Human Homologs

References

Homoserine O-acetyltransferase, involved in the Leptospira meyeri methionine biosynthetic pathway, is not feedback inhibited.
Bourhy P, Martel A, Margarita D, Saint Girons I, Belfaiza J
J Bacteriol 1997 Jul;179(13):4396-8
PubMed ID: 9209059