Pseudomonas aeruginosa PAO1, PA0394

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0394
Name
Synonym: yggS
Replicon chromosome
Genomic location 435663 - 436355 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249085.1
GI 15595591
Affymetrix PA0394_at
Entrez 878395
GenBank AAG03783.1
INSDC -
NCBI Locus Tag PA0394
protein_id(GenBank) gb|AAG03783.1|AE004476_13|gnl|PseudoCAP|PA0394
TIGR NTL03PA00395
UniParc UPI0000139731
UniProtKB Acc P24562
UniProtKB ID Y394_PSEAE
UniRef100 UniRef100_P24562
UniRef50 UniRef50_P24562
UniRef90 UniRef90_P24562

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.86
Kyte-Doolittle Hydrophobicity Value -0.088
Molecular Weight (kDa) 24.5
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 566 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000385 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0394

Human Homologs

Ensembl 110, assembly GRCh38.p14
pyridoxal phosphate binding protein [Source:HGNC Symbol;Acc:HGNC:9457]
E-value: 1.1e-25
Percent Identity: 38.5

References

Characterisation of a Pseudomonas aeruginosa twitching motility gene and evidence for a specialised protein export system widespread in eubacteria.
Whitchurch CB, Hobbs M, Livingston SP, Krishnapillai V, Mattick JS
Gene 1991 May 15;101(1):33-44
PubMed ID: 1676385