Pseudomonas aeruginosa PAO1, PA0405 (algH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0405
Name
algH
Synonym: yqgE
Replicon chromosome
Genomic location 446773 - 447342 (- strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249096.1
GI 15595602
Affymetrix PA0405_at
DNASU PaCD00006174
Entrez 878243
GenBank AAG03794.1
INSDC AAG03794.1
NCBI Locus Tag PA0405
protein_id(GenBank) gb|AAG03794.1|AE004477_11|gnl|PseudoCAP|PA0405
TIGR NTL03PA00406
UniParc UPI00000C4ED1
UniProtKB Acc Q9RQ16
UniProtKB ID ALGH_PSEAE
UniRef100 UniRef100_Q9RQ16
UniRef50 UniRef50_Q9RQ16
UniRef90 UniRef90_Q9RQ16

Product

Feature Type CDS
Coding Frame 1
Product Name
AlgH
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -9.39
Kyte-Doolittle Hydrophobicity Value -0.021
Molecular Weight (kDa) 20.2
Isoelectric Point (pI) 4.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2MUI UNKNOWN FUNCTION 09/10/14 Solution structure of the AlgH protein from Pseudomonas aeruginosa, PA0405, UPF0301 Pseudomonas aeruginosa NOT SOLUTION NMR 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 323 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000396 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0405
Search term: algH
Search term: AlgH

Human Homologs

References

Cloning, high yield overexpression, purification, and characterization of AlgH, a regulator of alginate biosynthesis in Pseudomonas aeruginosa.
Bieber Urbauer RJ, Gilmore JM, Rosasco SE, Hattle JM, Cowley AB, Urbauer JL
Protein Expr Purif 2005 Sep;43(1):57-64
PubMed ID: 16084397