Pseudomonas aeruginosa PAO1, PA0440

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0440
Name
Synonym: dypA
Replicon chromosome
Genomic location 493354 - 494721 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249131.1
GI 15595637
Affymetrix PA0440_at
Entrez 877574
GenBank AAG03829.1
INSDC AAG03829.1
NCBI Locus Tag PA0440
protein_id(GenBank) gb|AAG03829.1|AE004481_5|gnl|PseudoCAP|PA0440
TIGR NTL03PA00441
UniParc UPI00000C5057
UniProtKB Acc Q9I677
UniProtKB ID Q9I677_PSEAE
UniRef100 UniRef100_W0YKH8
UniRef50 UniRef50_Q3J1H4
UniRef90 UniRef90_S0I2C5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable oxidoreductase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -10.22
Kyte-Doolittle Hydrophobicity Value -0.097
Molecular Weight (kDa) 49.0
Isoelectric Point (pI) 5.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 536 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000431 (458 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0440

Human Homologs

Ensembl 86, assembly GRCh38.p7
dihydropyrimidine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3012]
E-value: 2.3e-51
Percent Identity: 34.3

References

Gene cloning, sequencing and enzymatic properties of glutamate synthase from the hyperthermophilic archaeon Pyrococcus sp. KOD1.
Jongsareejit B, Rahman RN, Fujiwara S, Imanaka T
Mol. Gen. Genet. 1997 May;254(6):635-42
PubMed ID: 9202379