Pseudomonas aeruginosa PAO1, PA0605 (agtC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0605
Name
agtC
Replicon chromosome
Genomic location 667108 - 668355 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249296.1
GI 15595802
Affymetrix PA0605_at
Entrez 878376
GenBank AAG03994.1
INSDC AAG03994.1
NCBI Locus Tag PA0605
protein_id(GenBank) gb|AAG03994.1|AE004497_1|gnl|PseudoCAP|PA0605
TIGR NTL03PA00606
UniParc UPI00000C50D5
UniProtKB Acc Q9I5T3
UniProtKB ID Q9I5T3_PSEAE
UniRef100 UniRef100_U8MH53
UniRef50 UniRef50_D3P3T7
UniRef90 UniRef90_A6UZA9

Product

Feature Type CDS
Coding Frame 1
Product Name
AgtC
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 12.61
Kyte-Doolittle Hydrophobicity Value 0.505
Molecular Weight (kDa) 45.9
Isoelectric Point (pI) 9.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 379 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000588 (518 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0605
Search term: agtC
Search term: AgtC

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Functional characterization of the agtABCD and agtSR operons for 4-aminobutyrate and 5-aminovalerate uptake and regulation in Pseudomonas aeruginosa PAO1.
Chou HT, Li JY, Lu CD
Curr Microbiol 2014 Jan;68(1):59-63
PubMed ID: 23982201