Pseudomonas aeruginosa PAO1, PA0683 (hxcY)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0683
Name
hxcY
Replicon chromosome
Genomic location 740203 - 741348 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
CommentHxc proteins are involved in the alkaline phosphatase secretion. May belong to the GspL family (general secretory pathway).

Cross-References

RefSeq NP_249374.1
GI 15595880
Affymetrix PA0683_at
Entrez 880821
GenBank AAG04072.1
NCBI Locus Tag PA0683
protein_id(GenBank) gb|AAG04072.1|AE004503_10|gnl|PseudoCAP|PA0683
TIGR NTL03PA00684
UniProtKB Acc Q9I5P2
UniProtKB ID Q9I5P2_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
HxcY
Product Name Confidence: Class 1
Synonyms probable type II secretion system protein
Evidence for Translation
Charge (pH 7) -2.66
Kyte-Doolittle Hydrophobicity Value -0.212
Molecular Weight (kDa) 39.8
Isoelectric Point (pI) 6.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 6 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000662 (361 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0683
Search term: hxcY
Search term: HxcY

Human Homologs

References

A novel type II secretion system in Pseudomonas aeruginosa.
Ball G, Durand E, Lazdunski A, Filloux A
Mol Microbiol 2002 Jan;43(2):475-85
PubMed ID: 11985723
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295